After an inmate violently escapes from a prison transport van, a witness from his murder trial is found dead; Megan investigates the original case when the fugitive claims he was framed.
When a gunman causes a deadly plane crash in Philadelphia, Megan and her team go into disaster mode; while Megan conducts autopsies during frequent blackouts, one body goes missing.
Megan arrives at the scene of a young girl’s murder and finds Tommy covered in blood; as evidence piles up against Tommy, Megan tries to ignore her doubts and prove his innocence.
During a murder investigation, a woman bites Tommy; Megan turns to the new health commissioner for help uncovering the truth behind strange rabies cases.
Kate falls for a handsome and mysterious man named Sergei at a political event; when a girl is murdered near the hotel where Kate and Sergei are staying, Kate thinks Sergei may be responsible.
While investigating a double murder committed by a vigilante killer, Megan questions a grief counselor who offers his services to help with issues concerning her father’s suicide.
Megan and and her team are shot at as they investigate a crime scene involving the murder of a notorious mobster’s son; after a suspect is gunned down, Megan realizes the case needs to be solved quickly before the body count rises.
A murder being investigated by Megan and Tommy appears to be the result of child abuse, but the victim’s parents claim their daughter was possessed and the devil killed her, and that he is now zeroing in on their other daughter.
Megan cracks the serial killer case but can’t reveal the answers to her team while Lacey’s life is in danger; District Attorney Dan Russell targets Kate.