The hospital staff get ready for a major storm about to hit Seattle. Meanwhile, Owen yearns to be a dad as he bonds with Ethan; Meredith and her unborn baby are put in peril; and Jo turns to Alex during a crisis.
Bailey continues to shut everyone out; Owen worries that Ethan could end up in foster care; a new craniofacial specialist comes to the hospital to work on a young patient; a magician’s assistant needs medical attention after a trick goes awry.
After several of Bailey’s patients die, she becomes the focus of a CDC investigation; Cristina teases Alex about his feelings for Jo; Owen continues to take care of Ethan while his parents remain in the hospital.
Unsettling news motivates Derek and Meredith to take preventative steps for their children’s future; Syrian doctors come to the hospital for a crash course in basic surgical skills; April decides to tell Matthew the truth.
As news of Seattle Grace’s financial issues spreads, Catherine wants Jackson to move to Boston and the interns fear for their jobs; the doctors try to save the hospital by meeting with a possible investor; Jo is impressed with Alex.