Artie has a few hurdles to overcome before he can get back to work; Pete and Claudia team up on a murder investigation involving a radical environmental group.
Brother Adrian resorts to extreme measures, sending deadly artifacts to the agents’ loved ones, to coerce Artie into reversing the Astrolabe’s effects. Meanwhile, Mrs. Frederic and Steve uncover something shocking during a trip to the Vatican
Pete and Myka uncover people who are rusting away in West Virginia. Meanwhile, Steve tries to quit his dependence on the Metronome by visiting his hometown; and Artie reveals the truth about Brother Adrian to Mrs. Frederic and H.G. Wells.
Pete and Myka face a curious executive from a drug company as they deal with a pill that may increase people’s height. Meanwhile, Artie, Steve and Claudia follow Brother Adrian to the place where he’s hiding.
Newell is still bent out of shape over an experience he and Fiona shared in college 20 years ago; and Putsy gets caught up in a legal entanglement. Later, a disappointed Fiona learns that an old flame may finally be over her.
Hugo resurfaces to help track down an artifact at his nephew’s prep school. Meanwhile, another artifact threatens the life of a musician in New Orleans.